We take a back-and-build approach to our investments, helping entrepreneurs access the human, intellectual, and financial resources needed to go the distance.

Alios BiopharmaClinical stage company focused on developing therapies for viral diseases
Decibel TherapeuticsGroundbreaking treatments to restore and improve hearing and balance
IpierianNovel treatments for Tauopathies
GroupAdvanced therapeutics for patients suffering from a range of autoimmune diseases
Pandion TherapeuticsTherapeutics for localized immunomodulation at the site of disease for patients with autoimmune and inflammatory disease
Principia BiopharmaOral treatments for immune diseases
GroupTaking a smarter approach to fertility and family building benefit solutions
River VisionBiologic to treat the thyroid eye disease
spero-colour-logoFocused on identifying, developing and commercializing medicines for multi-drug resistant (MDR) bacterial infections and rare disease
True North TherapeuticsDevelop novel therapeutics for complement-mediated rare diseases
Targeted cancer therapies designed to address treatment resistance and improve lives

NOTE: Referenced portfolio companies are provided for illustrative purposes only and this list may not be comprehensive, and it should not be assumed that any referenced portfolio companies were or will be profitable. Certain of these investments were made by the SR One team while part of the legacy business with GSK and are not in the Fund I or Fund II portfolios. Past performance is not a guarantee of future results. The views expressed on this website (a) are strictly those of SR One, (b) are for informational purposes only, (c) are not intended to provide a basis for evaluating any investment acquisition or disposition, (d) are not a recommendation of any particular investment or security, and (e) are not a recommendation to invest in any particular fund advised or managed by SR One.