Simeon is CEO of SR One. He joined the firm in 2007 and established the San Francisco office in 2010. He previously trained as a physician and worked in management consulting and investment banking. Simeon was formerly a Consultant at Bain & Co. and an Associate in the healthcare investment banking group of Goldman Sachs.
M.D., University of Pennsylvania School of Medicine
M.B.A., The Wharton School of Business, University of Pennsylvania B.A., Neuroscience, Johns Hopkins University
Board Representation: CRISPR Therapeutics (NASDAQ: CRSP), Nkarta (NASDAQ: NKTX), Turning Point Therapeutics (NASDAQ: TPTX), Design Therapeutics, eFFECTOR Therapeutics, Birdrock Bio and Rockend
Prior Board Representation: Principia Biopharma (Acquired by Sanofi), Progyny (NASDAQ: PGNY), Genocea (NASDAQ: GNCA), HTG Molecular (NASDAQ: HTGM), Semprus (Acquired by Teleflex)
Involved with: MiroBio Limited
Rajeev joined SR One in 2004 and is an alum of the Kauffman Fellows Program. Rajeev has previously worked in the Competitive Excellence group within GSK on company-wide strategic and operational projects. Rajeev has also worked at Genentech, where his role included technology and clinical development, and at Bio-Rad Laboratories in a product development role. In addition, he worked at Genome Therapeutics in business development and was a co-founder of Unimicro Technologies.
MBA, The Wharton School of Business, University of Pennsylvania
Ph.D., Chemistry, Stanford University
B.A., Math and Chemistry, Knox College
Board Representation: Avhana Health, Dren Bio, IlluminOss, Navitor Pharmaceuticals, Nimbus Therapeutics, Palleon Pharmaceuticals, Tranquis Therapeutics
Prior Board Representation: Adheron (acquired by Roche), Concert (NASDAQ: CNCE), Cydex (acquired by Ligand), iPierian (acquired by BMS), NeuroTherapeutics Pharma, Propeller (acquired by ResMed), True North (acquired by Bioverativ)
Matthew joined SR One’s London office in 2011. Previously he spent eight years at Greenhill & Co, an M&A Investment Bank and Private Equity firm in New York.
Biological Sciences – Molecular biology, Genetics and Statistics – University of Oxford
Corporate Finance – London Business School
Drug Discovery – University College London
Board Representation: AtoxBio, Decibel Therapeutics, NovellusDx, PsiOxus, Pulmocide, Rockend, VHSquared
Prior Board Representation: Atopix, Puridify (acquired by GE)
Involved with: Asceneuron
Jill joined SR One in 2011 with a background in biotech partnering and corporate development. Previously, she completed multiple pharma partnerships and substantial private and public financings at Dynavax Technologies (NASDAQ: DVAX). Jill was formerly a biopharmaceutical industry consultant at Clearview Projects and Mercer Management Consulting.
M.S., Biochemistry, Cellular and Molecular Biology, Johns Hopkins University
B.S., Chemistry, Duke University
Board Representation: Pandion (NASDAQ: PAND), Arcellx, HotSpot Therapeutics
Prior Board Representation: Alios (acquired by JNJ), Nkarta (NASDAQ: NKTX), Tioma Therapeutics
Involved with: AGTC (NASDAQ: AGTC), eFFECTOR, Progyny, Principia Biopharma (NASDAQ: PRNB), 858 (formerly Gotham Therapeutics), Second Genome
Debbie joined SR One in 2005 to establish the European investment office with a background in drug development and licensing gained through numerous prior roles held in clinical development, medical affairs and business development with Merrell Dow, SmithKline Beecham and GSK. Debbie is also an independent director on the board of Cancer Research Technology, the commercialization arm of Cancer Research UK and a member of the Advisory Board of the University of Cambridge Maxwell Centre’s ‘Impulse’ program for young entrepreneurs.
MBA, Henley Management College
Ph.D., Pharmacology, University of London
B.Sc. (Hons) Pharmacology, University of Bath
Board Representation: Asceneuron, AtoxBio, F-star, MiroBio, Mission Therapeutics, Pulmocide, PsiOxus, VHsquared
Prior Board Representation: 7TM Pharma, Ablynx (EURONEXT:ABLX; acquired by Sanofi), Addex Therapeutics (SIX:ADXN), Atopix Therapeutics (acquired by Chiesi), Bicycle Therapeutics (NASDAQ:BCYC), Pharmakodex, Syntaxin (acquired by Ipsen)
Involved with: Genocea (NASDAQ:GNCA), HotSpot Therapeutics
Rodger is a consultant for SR One. He joined the firm in 2020 and works in Switzerland. He is a trained physician and has worked for almost 20 years as senior executive in the industry; more recently as Global Head Anti-Infectives R&D at Sanofi and former CEO and now Chair of the Board of CRISPR Therapeutics. Before his career in pharma he was in academia in leading US research institutions like The Rockefeller University. He became a tenured professor in microbiology at the Vienna Biocenter in 2001.
M.D., Philipps University, Marburg, Germany
Current Board Representation: CRISPR Therapeutics (NASDAQ: CRSP) (Chair), Rockend (Chair)
Eliot is a Venture Partner with SR One. He joined the firm in 2019 and works in the London office. He is a founder and Executive Chairman at MiroBio and an advisor to Rockend. Eliot started his career at Genentech and later led Amgen’s External R&D Affairs group. He has also been Partner and Venture Partner at Apax Partners and New Leaf Venture Partners, respectively. Eliot was also the founding COO of Prinicipia Biopharma.
Ph.D., Brain and Cognitive Sciences, MIT
M.B.A., University of Chicago, GSB
Heather joined SR One in 2019. Previously, she worked as a Principal at Sofinnova Ventures, and prior to that, as an Equity Research Analyst at two boutique Investment Banks. Heather was formally a Chemist at the Astellas Research Institute and Adjunct Faculty at Northwestern University.
Ph.D., Chemistry, Northwestern University
MSc., Organic Chemistry, Weizmann Institute of Science
B.S., Biopsychology, Tufts University
Board Representation: Second Genome, Dren Bio (Board Observer)
Involved with: Design Therapeutics, MiroBio
Amit started at S. R. One in January 2018. Prior to this, he worked in late phase R&D clinical development, global medical affairs, and early pipeline commercial strategy at GSK. Before joining GSK in March 2016, he practiced as a plastic surgeon for ten years in London, having specialized in head and neck, breast, and perineal cancer reconstruction.
M.D., University of Cambridge, UK
M.A., Neuroscience, University of Cambridge, UK
Current Board Representation: Gladius Pharma, HotSpot Therapeutics (Board Observer), IlluminOss (Board Observer)
Prior Board Representation: CalciMedica
Involved with: Principia Biopharma (NASDAQ: PRNB), Nkarta (NASDAQ: NKTX), and eFFECTOR Therapeutics
Karen joined SR One in 2002. She brings a range of experience to SR One, including extensive contract, legal and finance experience gained through various positions held at Quest Diagnostics, SmithKline Beecham Clinical Laboratories, and Shared Medical Systems.
MBA, LaSalle University
B.A., Political Science, Bloomsburg University
Previously involved with: Avhana Health, Scynexis (NASDAQ: SCYX), NuPathe (acquired by Teva Pharmaceuticals) and Rib-X Pharmaceuticals now Melinta Therapeutics (NASDAQ: MLNT)
James is Finance Director at SR One based in London. He joined the firm in 2020 having led the financial reporting and spin-out workstreams for SR One over the course of 2019. Previously, James spent 3 years within the GSK Group in roles including finance lead for the Pharma business in Finland and in corporate finance in London.
MBA, HEC Paris
University of Oxford
University of Cambridge
Philip joined SR One in 2020 and leads the firm’s Capital Partnering effort. He has more than 12 years of experience in Venture capital, Private equity, and Real Estate.
Philip was formerly in the Business Development (M&A) and the Leveraged Finance groups at General Electric, and began his career as a private equity and venture capital consultant at Cambridge Associates, the leading investment advisory firm.
M.A. Economics, The University of Edinburgh
M.B.A., London Business School
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