CalciMedica (USA) is dedicated to the discovery and development of novel small molecule drugs for the treatment of autoimmune and inflammatory diseases. A significant focus of the company’s drug discovery strategy is based on the specific inhibition of calcium release-activated calcium (CRAC) channels.


http://www.calcimedica.com

CoNCERT Pharmaceuticals, Inc (USA) creates new drugs by using precision deuterium chemistry to modify the pharmacology of existing and new small molecule compounds to create a treatment benefit.


http://www.concertpharma.com
CyDex (USA) develops and commercializes specialty pharmaceutical products based on drug delivery and formulation technologies.
http://www.cydexinc.com
Locus Pharmaceuticals, Inc. (USA) applies its core fragment-based, computational drug design technology with its capabilities in medicinal chemistry, crystallography and biology to create small molecule product.  The company has a portfolio of emerging candidates in development for cancer and inflammation.
http://www.locuspharma.com
Novalar Pharmaceuticals, Inc.(USA)  is a specialty pharmaceutical company. Lead asset NV-101, for the reversal of numbness associated with local dental anesthesia, has completed Phase III trials. An NDA was filed in 2007.
http://www.novalarpharm.com
Nucleonics, Inc. (USA) is a drug discovery and development company that is using proprietary RNAi technologies for the treatment of infectious and other diseases.
http://www.nucleonicsinc.com
Protez Pharmaceuticals (USA) discovers and develops new anti-microbials to combat the growing problem of drug resistance, as well as agents that improve the efficacy of current antibiotics.
http://www.protez.com
Rib-X Pharmaceuticals (USA) is developing novel classes of anti-microbials to address unmet needs in resistant community and hospital-acquired infections using structure-based drug design and its proprietary knowledge of the crystal structure of the 50S subunit of the ribosome and other important targets.
http://www.rib-x.com
Scynexis, Inc. (USA) offers drug discovery and development services to biotech and pharmaceutical companies through a suite of research, development and products.
http://www.scynexis.com
Trinity Biosystems (USA) is using its novel platform of oral and nasal delivery to develop proteins and peptide therapeutics.
http://www.trinitybiosystems.com
Zelos Therapeutics (USA)  is developing new treatments for osteoporosis and other indications based on breakthrough discoveries in parathyroid hormone research. Lead candidate Ostabolin C is in Phase II trials.
http://www.zelostherapeutics.com