Ablynx (Belgium) is engaged in the discovery and development of  Nanobodies®, a novel class of therapeutic proteins based on single-domain antibody fragments, for a range of serious human diseases including inflammation, thrombosis, oncology and Alzheimer’s disease. 
http://www.ablynx.com
Addex (Switzerland) discovers and develops novel therapeutics which modulate the effect of natural activators of G-protein coupled receptors on their specific targets. These allosteric modulators offer the potential for novel, more selective and safer treatments for CNS and other disorders.
http://www.addexpharma.com
Algeta ASA (Norway) develops alpha particle emitters as radio-
pharmaceuticals for the treatment of prostate cancer and other metastatic tumor types for which there is substantial unmet medical need.
http://www.algeta.no
Anesiva (USA) is a late-stage biopharmaceutical company that seeks to be the leader in the development and commercialization of novel therapeutic treatments for pain.
http://www.anesiva.com/
EPIX Pharmaceuticals (USA) is a biopharmaceutical company focused on discovering and developing novel therapeutics through the use of its proprietary and highly efficient in silico drug discovery platform
http://www.epixpharma.com/
Kosan Biosciences (USA) is a therapeutics company focused on advancing two new classes of anticancer agents through clinical development: heat shock protein 90 (Hsp90) inhibitors and epothilones.
http://www.kosan.com/
Lexicon (USA) is a biopharmaceutical company focused on the discovery and development of breakthrough treatments for human disease. The company uses its proprietary gene knockout technology to disrupt the function of genes in mice and then employs an integrated platform to systematically discover the physiological and behavioral functions and pharmaceutical utility of the genes.
http://www.lexpharma.com/index.php
Memory Pharmaceuticals (USA) is a biotechnology company focused on developing innovative drugs for the treatment of debilitating central nervous system (CNS) disorders, many of which exhibit significant impairment of memory and other cognitive function. 
http://www.memorypharma.com/
OctoPlus NV (Netherlands) provides formulation services and develops proprietary products employing its patented implantable polymer microspheres for controlled drug delivery.
http://www.octoplus.nl
RedPoint Bio. (USA) develops gustation solutions, with a
focus on products to improve bitter flavors and treatments
for taste dysfunction.
http://www.redpointbio.com
TorreyPines Therapeutics (USA) is a biopharmaceutical company committed to discovering, developing and commercializing novel small molecules to treat diseases and disorders of the central nervous system.
http://www.torreypinestherapeutics.com/home.php